ea0092op-04-06 | Oral Session 4: Young Investigators / Clinical and Translational | ETA2023
Links Mirthe
, Lefrandt Joop
, Van Der Boom Trynke
, Willems Tineke
, van der Meer Peter
, Links Thera
, Zandee Wouter
Background: Differentiated thyroid carcinoma (DTC) survivors have an increased risk of cardiovascular mortality but, the pathophysiological mechanism remains largely unknown. Early treatment for high-risk DTC entails thyroid surgery, radioiodine therapy with thyroid hormone (TH)-withdrawal, and thyroxine suppression therapy (THST). During treatment, patients cycle from severe hypothyroidism to exogenous subclinical hyperthyroidism. TH changes in early DTC treatment might affec...